Effect of Prophylactic Tranexamic Acid on Bleeding Outcomes for Dilation and Evacuation

Summary

Prophylactic tranexamic acid has shown been shown to reduce maternal mortality from postpartum hemorrhage with no adverse effects, but has not been studied to reduce bleeding complications with dilation and evacuation (D\&E). We propose a randomized, double-blinded, placebo-controlled pilot study to determine whether routine use of intravenous (IV) tranexamic acid will decrease the need for interventions to control bleeding at the time of D\&E at 16 to 24 weeks gestation.

Timeline

Start

2022-02-15

Primary completion

2023-07-27

Completion

2023-07-27

Drugs

Indications