drugset / Trial / NCT04656262
Low Dose Continuous Cyclophosphamide vs Standard Doxorubicin in Advanced Sarcoma Elderly Patients
Phase 3
Terminated
79 enrolled
Veneto Institute of Oncology IRCCS
Ministry of Health, Italy · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
To compare the efficacy, as measured by time to treatment failure, of metronomic cyclophosphamide with respect to doxorubicin in elderly patients affected by mSTS.
Timeline
- Start
- 2018-09-10
- Primary completion
- 2024-05-23
- Completion
- 2024-05-23
Outcome
Outcome not reported
Stopped (Enrollment): “enrollment too slow to reach the target in a reasonable time frame”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cyclophosphamide | Other / unclassified | 50 mg | Oral |
| Comparator | Doxorubicin | Other / unclassified | 60 mg/m2 | Intravenous |