drugset / Trial / NCT04658836

Triamcinolone Levels in Cochlear Perilymph, Lateral Canal and CSF

NCT04658836

Phase 1 Completed 21 enrolled Medical University of Vienna
NaSingle-groupOpen-labelTreatment

Summary

Patients undergoing surgery of a vestibular schwannoma will be included in the study. Patients will receive triamcinolone acetonide 24h before surgery. During translabyrinthine surgery cochlear perilymph, perilymph from the semicircular canal and cerebrospinal fluid will be taken and analyzed for triamcinolone content. In patients undergoing middle fossa or retrosigmoid resection only cerebrospinal fluid will be taken and analyzed for triamcinolone acetonide level.

Timeline

Start
2020-02-01
Primary completion
2021-08-31
Completion
2021-10-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Triamcinolone Acetonide Other / unclassified 40 mg/ml Other

Indications