drugset / Trial / NCT04678050
Dexmedetomidine Compared to Ketofol for Sedation in Paediatrics
RandomizedParallel-groupQuadruple-blindSupportive care
Summary
Dental fear and anxiety remain common problems that should be managed by both the dentist and the anesthetist. The currently available evidence for safe and effective sedative drugs for children undergoing the dental procedure is scarce The aim of this study was to compare the safety and efficacy of intravenous ketofol versus dexmedetomidine (Dex) as premedications a sedative in anxious children undergoing dental pulp therapy
Timeline
- Start
- 2020-10-10
- Primary completion
- 2021-12-10
- Completion
- 2021-12-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dexmedetomidine | Other / unclassified | 0.1 ug/kg | Intravenous |
| Comparator | Dexmedetomidine | Other / unclassified | 1 ug/kg | Intravenous |
| Comparator | Dexmedetomidine | Other / unclassified | 4 ug/ml | Intravenous |
| Comparator | Ketamine | Small molecule | 5 mg/ml | Intravenous |
| Comparator | Propofol | Small molecule | 10 mg/ml | Intravenous |
Indications
No indication recorded.