drugset

drugset / Trial / NCT04679818

Postoperative Consequences of Intraoperative NOL Titration

NCT04679818 ↗

Phase 3 Completed 72 enrolled The Cleveland Clinic

RandomizedParallel-groupDouble-blindPrevention

Summary

To demonstrate that intraoperative NOL-guided titration of fentanyl improves initial recovery characteristics.

Timeline

Start: 2020-12-30
Primary completion: 2022-12-30
Completion: 2023-01-10

Publications

Ruetzler K, Montalvo M, Bakal O, Essber H, Rossler J, Mascha EJ, Han Y, Ramachandran M, Keebler A, Turan A, Sessler DI. Nociception Level Index-Guided Intraoperative Analgesia for Improved Postoperative Recovery: A Randomized Trial. Anesth Analg. 2023 Apr 1;136(4):761-771. doi: 10.1213/ANE.0000000000006351. Epub 2023 Jan 20.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Fentanyl	Other / unclassified	1 ug/kg	—

Indications

No indication recorded.