drugset / Trial / NCT04682691

Effect of Metoclopramide Versus Erythromycin on on Gastric Residual Volume

NCT04682691

Completed 50 enrolled Cairo University
RandomizedParallel-groupQuadruple-blindPrevention

Summary

In emergencies, it may be necessary to anaesthetize who are not fully starved and consequently at risk of pulmonary aspiration. Pregnancy are recognized to be at increased risk of aspiration compared with non-pregnancy. Prokinetic agents such as metoclopramide can be used to reduce GRV. Metoclopramide is widely used as a prokinetic agent in adults and is licensed for premedication in pregnancy, but its use may be limited by its potential for producing extrapyramidal side effects. Erythromycin is an effective prokinetic agent in adults but there is no work examining its use for premedication in pregnancy. This study compared the effects of erythromycin and metoclopramide on GRV in full-term pregnant women

Timeline

Start
2021-03-01
Primary completion
2024-02-05
Completion
2024-02-22

Drugs

EvaluationDrugModalityDoseRoute
Comparator Erythromycin Small molecule 400 mg Oral
Comparator Metoclopramide Small molecule 10 mg Oral

Indications

No indication recorded.