drugset / Trial / NCT04685070

Neoadjuvant HS-10296 (Almonertinib) Therapy for Potential Resectable Stage III EGFR Mutation-Positive Non-small Cell Lung Cancer

NCT04685070

Phase 2 Active not recruiting 56 enrolled Shanghai Pulmonary Hospital, Shanghai, China
NaSingle-groupOpen-labelTreatment

Summary

This is a phase II, single-arm, open-label study to evaluate the efficacy and safety of the third generation tyrosine kinase inhibitors (TKIs) Almonertinib (HS-10296) as neoadjuvant and adjuvant therapy for potential resectable stage III EGFR mutation-positive Non-small Cell Lung Cancer.

Timeline

Start
2021-12-14
Primary completion
2022-12-31
Completion
2027-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Almonertinib Small molecule 110 mg Oral