drugset / Trial / NCT04697576
Intralesional Influenza Vaccine for the Treatment of Stage I-IV Melanoma
Non-randomizedParallel-groupOpen-labelTreatment
Summary
This phase I trial investigates the effects of influenza vaccine in treating patients with stage I-IV melanoma. While intramuscular administration of influenza vaccine provides immunization against the influenza virus, giving influenza vaccine directly into the tumor (intralesional) may decrease the size of the injected melanoma tumor, or the extent of the melanoma within the body.
Timeline
- Start
- 2021-10-20
- Primary completion
- 2027-09-30
- Completion
- 2027-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Quadrivalent Inactivated Influenza Vaccine | Vaccine | — | Intramuscular |
| Background | Ipilimumab | Monoclonal antibody | — | — |
| Background | Nivolumab | Monoclonal antibody | — | — |
| Background | Pembrolizumab | Monoclonal antibody | — | — |
| Background | Relatlimab | Monoclonal antibody | — | — |