drugset / Trial / NCT04700527
The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of this study is to assess and compare GI toxicity from RT between subjects who receive therapeutic SCFA and those who receive placebo, in hopes of identifying a safe, low-cost therapeutic to reduce GI toxicity from therapeutic or environmental radiation.
Timeline
- Start
- 2023-12-15
- Primary completion
- 2027-04-21
- Completion
- 2031-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Sodium Butyrate | Small molecule | 4 g | Oral |
| Comparator | Sodium Butyrate | Small molecule | 6 g | Oral |
| Comparator | Sodium Propionate | Small molecule | 4 g | Oral |
| Comparator | Sodium Propionate | Small molecule | 6 g | Oral |