drugset / Trial / NCT04705584

Topical Immuonosuppressant Drugs in Spring Catarrh

NCT04705584

Unknown 180 enrolled Assiut University
RandomizedParallel-groupOpen-labelTreatment

Summary

Spring catarrh is a prevalent type of conjunctival allergic disorder in temperate countries. Topical steroids are the cornerstone management of spring catarrh beside other anti allergic drugs. However, prolonged use of topical steroids especqially in resistant spring catarrh carries risk of ocular side effects as 2nd glaucoma and cataract. We will investigate the safety and efficacy of topical immuonosuppressant in the management of resistant spring catarrh as an alternative to steroid therapy.

Timeline

Start
2021-01
Primary completion
2021-10
Completion
2022-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Cyclosporine Peptide 2 % Topical
Comparator Prednisolone Other / unclassified 1 % Topical
Subject Tacrolimus Small molecule 0.3 % Topical