drugset / Trial / NCT04709731

Cardiovascular Assessment of Ponatinib as Third Line Treatment in Chronic Phase Chronic Myeloid Leukemia

NCT04709731

NaSingle-groupOpen-labelTreatment

Summary

This study will address the therapeutic activity and the safety/biological profile of Ponatinib when used as third line therapy of Chronic Myeloid Leukemia in Chronic Phase after the only two TKIs known for their cardiovascular safety, i.e. Imatinib and Bosutinib.

Timeline

Start
2021-02-01
Primary completion
2024-10-31
Completion
2025-04-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Ponatinib Small molecule 15 mg Oral
Subject Ponatinib Small molecule 30 mg Oral