drugset / Trial / NCT04718922
Chlorhexidine Mouthrinse Before EBUS-TBNA
RandomizedParallel-groupTriple-blindPrevention
Summary
The purpose of this study is to investigate whether chlorhexidine mouthrinse is effective in preventing microbial contamination during endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA).
Timeline
- Start
- 2021-01-20
- Primary completion
- 2021-06-11
- Completion
- 2021-12-11
Outcome
Missed primary endpoint
paper The median CFU counts of needle wash samples in aerobic cultures were not significantly different in the two groups (10 CFU/mL vs 20 CFU/mL; P = 0.70). PMID 36539736 ↗
Publications
- Kim NY, Park JH, Park J, Kwak N, Choi SM, Park YS, Lee CH, Cho J. Effect of chlorhexidine Mouthrinse on prevention of microbial contamination during EBUS-TBNA: a randomized controlled trial. BMC Cancer. 2022 Dec 20;22(1):1334. doi: 10.1186/s12885-022-10442-5.
- Kim NY, Park JH, Park J, Kwak N, Choi SM, Park YS, Lee CH, Cho J. Effect of Chlorhexidine Mouthrinse on Prevention of Microbial Contamination during EBUS-TBNA: A Study Protocol for a Randomized Controlled Trial. Tuberc Respir Dis (Seoul). 2021 Oct;84(4):291-298. doi: 10.4046/trd.2021.0058. Epub 2021 Jun 24.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Chlorhexidine gluconate | Other / unclassified | 0.12 % | Other |
Indications
No indication recorded.