drugset / Trial / NCT04723732

Antiplaque, Antigingivitis and Anti-inflammatory Effects of Myrrh Mouthwash

NCT04723732

Completed 24 enrolled King Abdulaziz University
RandomizedParallel-groupTriple-blindTreatment

Summary

Myrrh-based mouthwash has the potential to be a suitable alternative to the gold standard chlorhexidine mouthwash for dental plaque and gingivitis reduction. To date, however, little research has been carried out to determine its true clinical significance on periodontal health. The purpose of this study is to evaluate and compare the efficacy of 1% myrrh mouthwash with commercially available 0.2% chlorhexidine mouthwash in terms of plaque and gingivitis reduction and inflammatory mediator (interleukin-1β) inhibition.

Timeline

Start
2017-08-15
Primary completion
2018-08-15
Completion
2018-12-15

Drugs

EvaluationDrugModalityDoseRoute
Comparator Chlorhexidine Small molecule 0.2 % Oral
Subject Myrrh Traditional medicine (herbal / TCM) 1 % Oral