drugset / Trial / NCT04723732
Antiplaque, Antigingivitis and Anti-inflammatory Effects of Myrrh Mouthwash
RandomizedParallel-groupTriple-blindTreatment
Summary
Myrrh-based mouthwash has the potential to be a suitable alternative to the gold standard chlorhexidine mouthwash for dental plaque and gingivitis reduction. To date, however, little research has been carried out to determine its true clinical significance on periodontal health. The purpose of this study is to evaluate and compare the efficacy of 1% myrrh mouthwash with commercially available 0.2% chlorhexidine mouthwash in terms of plaque and gingivitis reduction and inflammatory mediator (interleukin-1β) inhibition.
Timeline
- Start
- 2017-08-15
- Primary completion
- 2018-08-15
- Completion
- 2018-12-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Chlorhexidine | Small molecule | 0.2 % | Oral |
| Subject | Myrrh | Traditional medicine (herbal / TCM) | 1 % | Oral |