drugset / Trial / NCT04730245

Microbiota Modification for the Treatment of Motor Complication of Parkinson´s Disease

NCT04730245

Phase 1 Completed 14 enrolled Torre Médica Santé
NaSingle-groupOpen-labelTreatment

Summary

In recent years, abnormalities in gut microbiota have been identified in patients with Parkinson´s disease having a possible role in motor manifestations. Among 80 patients with PD, we selected 14 with LID and motor fluctuations with limited response to pharmacological therapy to receive treatment with sodium phosphate enema, oral rifaximin and polyethylene glycol to improve motor complications.

Timeline

Start
2018-06-01
Primary completion
2020-03-30
Completion
2020-03-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Rifaximin Other / unclassified 200 mg Oral
Subject polyethylene glycol Other / unclassified 17 g Oral
Subject sodium phosphate Unknown Rectal

Indications