drugset / Trial / NCT04730401

Convalescent Plasma in the Treatment of Covid-19

NCT04730401

RandomizedParallel-groupTriple-blindTreatment

Summary

This study investigates the possible adverse effects and effectiveness of convalescent plasma for patients infected with SARS-CoV-2. Following provision of informed consent, patients will be randomized into three groups: High-titre convalescent plasma, low-titre convalescent plasma or placebo. Primary outcomes of the study will cover safety and either intubation or initiation of systemic corticosteroids. Safety information collected will include serious adverse events judged to be related to administration of convalescent plasma. Microbiological and other laboratory parameters will be followed up.

Timeline

Start
2021-01-27
Primary completion
2022-01-30
Completion
2023-01-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Convalescent Plasma Protein / enzyme biologic 200 ml

Indications