drugset / Trial / NCT04730401
Convalescent Plasma in the Treatment of Covid-19
Phase 2
Unknown
390 enrolled
Helsinki University Central Hospital
Finnish Red Cross Blood Service · collab
RandomizedParallel-groupTriple-blindTreatment
Summary
This study investigates the possible adverse effects and effectiveness of convalescent plasma for patients infected with SARS-CoV-2. Following provision of informed consent, patients will be randomized into three groups: High-titre convalescent plasma, low-titre convalescent plasma or placebo. Primary outcomes of the study will cover safety and either intubation or initiation of systemic corticosteroids. Safety information collected will include serious adverse events judged to be related to administration of convalescent plasma. Microbiological and other laboratory parameters will be followed up.
Timeline
- Start
- 2021-01-27
- Primary completion
- 2022-01-30
- Completion
- 2023-01-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Convalescent Plasma | Protein / enzyme biologic | 200 ml | — |