drugset / Trial / NCT04735978
Study of RP3 Monotherapy and RP3 in Combination With Nivolumab in Patients With Solid Tumours
Non-randomizedSequentialOpen-labelTreatment
Summary
This is a Phase 1, multicenter, open label, single agent dose escalation and combination treatment study of RP3 in adult participants with advanced solid tumors, to evaluate the safety and tolerability of RP3 both as a single agent and in combination with anti-PD1 therapy and to determine the recommended Phase 2 dose (RP2D) of RP3.
Timeline
- Start
- 2020-12-29
- Primary completion
- 2026-11-30
- Completion
- 2026-11-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Nivolumab | Monoclonal antibody | — | — |
| Subject | RP3 | Unknown | 1e+06 unknown | Other |
| Subject | RP3 | Unknown | 1e+07 unknown | Other |