drugset / Trial / NCT04736810

A Study of Penpulimab Combination Therapy in Patients With Advanced Nasopharyngeal Carcinoma

NCT04736810

Phase 2 Completed 28 enrolled Akeso Akeso Tiancheng, Inc · collab
NaSingle-groupOpen-labelTreatment

Summary

This is a multi-center, randomized, open-label, phase II study to evaluate the efficacy and safety of anti-PD-1 antibody Penpulimab (AK105) combined with chemotherapy ± anlotinib hydrochloride in the first-line treatment of patients with advanced nasopharyngeal carcinoma.

Timeline

Start
2021-02-25
Primary completion
2022-06-09
Completion
2023-12-18

Drugs

EvaluationDrugModalityDoseRoute
Subject Catequentinib Small molecule Oral
Subject Cisplatin Other / unclassified Intravenous
Subject Gemcitabine Small molecule Intravenous
Subject Penpulimab Monoclonal antibody Intravenous