drugset / Trial / NCT04737343
Comparison of the Efficacy of Leflunomide and Azathioprine for the Maintenance Therapy of ANCA Associated Vasculitis
Unknown
114 enrolled
Chinese SLE Treatment And Research Group
Affiliated Hospital of Jilin University, Changchun,China · collabBeijing Shijitan Hospital, Capital Medical University · collabFirst Affiliated Hospital of Kunming Medical University · collabSecond Affiliated Hospital of Nanchang University · collabSecond Affiliated Hospital, School of Medicine, Zhejiang University · collabShanghai Zhongshan Hospital · collabSichuan Province People's Hospital · collabThe Affiliated Hospital of Inner Mongolia Medical University · collabThe First Affiliated Hospital of Anhui Medical University · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
This study is a prospective, open-labelled, randomized, controlled,multi-center clincial trial. The aim of this study is to verify that the remission rate of patients treated with Leflunomide is not inferior to that of patients treated with Azathioprine.
Timeline
- Start
- 2021-06-30
- Primary completion
- 2024-11-30
- Completion
- 2024-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Azathioprine | Small molecule | 100 mg | — |
| Subject | Leflunomide | Small molecule | 30 mg | — |