drugset / Trial / NCT04741945
Repurposing Metformin As a Leukemia-preventive Drug in CCUS and LR-MDS
Phase 2
Recruiting
40 enrolled
Kirsten Grønbæk
Herlev Hospital · collabRegion Hovedstadens Apotek · collabSteno Diabetes Center Copenhagen · collabTechnical University of Denmark · collabUniversity of Copenhagen · collabVan Andel Research Institute · collabZealand University Hospital · collab
NaSingle-groupOpen-labelOther
Summary
This is a single-arm pilot study of the feasibility and safety of metformin in patients with clonal cytopenia of undetermined significance (CCUS) or lower-risk myelodysplastic neoplasms (LR-MDS).
Timeline
- Start
- 2021-12-13
- Primary completion
- 2026-02
- Completion
- 2026-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Metformin | Small molecule | 2000 mg | — |