drugset / Trial / NCT04747080
The Combination of Tacrolimus and High-dose Dexamethasone as First-line Treatment in Adult Immune Thrombocytopenia
Phase 2
Unknown
120 enrolled
Peking University People's Hospital
Beijing Friendship Hospital · collabBeijing Hospital · collabChina-Japan Friendship Hospital · collabFirst Affiliated Hospital of Chongqing Medical University · collabShanxi Bethune Hospital · collabThe First Affiliated Hospital of Zhengzhou University · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
Randomized, open-label, multicenter study to compare the efficacy and safety of Combination of High-dose Dexamethasone and Tacrolimus versus High-dose Dexamethasone for the first-line treatment of adults with primary immune thrombocytopenia (ITP).
Timeline
- Start
- 2021-03-01
- Primary completion
- 2023-03-01
- Completion
- 2023-07-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Tacrolimus | Small molecule | 0.03 mg/kg | — |
| Background | Dexamethasone | Small molecule | 40 mg | — |