drugset / Trial / NCT04748562

Vaginal Progesterone 400mg v.s 200mg for Prevention of Preterm Labor in Twin Pregnancies

NCT04748562

Phase 4 Completed 100 enrolled Ain Shams University
RandomizedParallel-groupOpen-labelPrevention

Summary

It is already known that the risk of preterm labor in twin pregnancy before 37 week is 8-9 fold higher compared to singletons, and progesterone supplementation can decrease the incidence of preterm labor in singleton pregnancy. There were studies that used 200mg vaginal progesterone with no effect on the result So this study aims To examine the effect of prophylactic vaginal progesterone 400mg v.s 200mg for prevention of preterm birth in twin pregnancies

Timeline

Start
2020-01-01
Primary completion
2020-08-01
Completion
2020-12-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Progesterone Other / unclassified 200 mg Other
Comparator Progesterone Other / unclassified 400 mg Other

Indications