drugset / Trial / NCT04758871

Oral Versus Vaginal Progesterone for Luteal Phase Supplementation in Frozen Embryo Transfer Cycles

NCT04758871

Phase 4 Completed 150 enrolled CRG UZ Brussel
RandomizedParallel-groupOpen-labelTreatment

Summary

To investigate the efficacy of dydrogesterone 30 mg compared to micronized vaginal progesterone 800 mg daily for luteal phase support in hormone replacement therapy frozen embryo transfer cycles, as confirmed by visualization of fetal heart activity by pelvic ultrasound assessment of ongoing pregnancy at 12 weeks of gestation.

Timeline

Start
2021-10-01
Primary completion
2023-09-11
Completion
2024-06-13

Drugs

EvaluationDrugModalityDoseRoute
Subject Dydrogesterone Other / unclassified 10 mg Oral
Comparator Progesterone Other / unclassified 400 mg Intravenous

Indications