drugset / Trial / NCT04763044

Evaluation of the Fluoride Dose Response Using In Situ Caries Model

NCT04763044

Phase 4 Completed 15 enrolled Procter and Gamble
RandomizedCrossoverDouble-blindOther

Summary

The purpose of this study is to evaluate the fluoride dose response of different dentifrice fluoride concentrations - 0, 250, 1100 and 2800 ppm fluoride as sodium monofluorophosphate (MFP) and a fifth leg of 1100 ppm Stannous Fluoride (SnF2) using an in situ caries model.

Timeline

Start
2021-03-01
Primary completion
2021-07-21
Completion
2021-07-21

Drugs

EvaluationDrugModalityDoseRoute
Subject 250 ppm F as MFP Unknown 250 ppm
Subject 250 ppm F as MFP Unknown 1100 ppm
Subject 250 ppm F as MFP Unknown 2800 ppm
Subject stannous fluoride Small molecule 1100 ppm

Indications