drugset / Trial / NCT04763486

Prophylactic Antibiotic After Perineal Tear

NCT04763486

Unknown 2500 enrolled Meir Medical Center
RandomizedParallel-groupOpen-labelPrevention

Summary

Current World Health Organization guidelines recommend routine antibiotic prophylaxis for women with perineal tear 3rd and 4th degree but not for 2nd degree because of insufficient evidence of effectiveness. The investigators aimed to investigate whether antibiotic prophylaxis prevented maternal infection after the first and second perineal tear after vaginal birth.

Timeline

Start
2021-03-01
Primary completion
2022-03-01
Completion
2023-03-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Cefazolin Small molecule 2 g Intravenous

Indications