drugset / Trial / NCT04768179
Safety & Efficacy of Low Dose Aspirin / Ivermectin Combination Therapy for Treatment of Covid-19 Patients
Phase 2/3
Unknown
490 enrolled
Makerere University
Joint Clinical Research Center · collabMbarara University of Science and Technology · collabMinistry of Health, Uganda · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
COVID-19, caused by the novel Severe Acute Respiratory Syndrome Corona Virus 2 (SARSCoV-2), has become a global pandemic. Fortunately, most of the COVID-19 cases confirmed are categorized as mild for whom home- based symptomatic management with monitoring of clinical deterioration is recommended. Despite providing symptomatic management, a therapeutic drug that would limit the course of infection is greatly needed to stop COVID-19 disease progression. Considering the current SARS-CoV-2 epidemiology and the legitimate rash towards appropriate therapies, our study seeks to evaluate the safety and efficacy of low dose aspirin and ivermectin combination therapy in COVID-19 patients.
Timeline
- Start
- 2021-02-19
- Primary completion
- 2021-06-30
- Completion
- 2021-09-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Aspirin | Small molecule | 75 mg | — |
| Subject | Ivermectin | Small molecule | 200 ug/kg | — |
| Subject | Ivermectin | Small molecule | 600 ug/kg | — |