drugset / Trial / NCT04773756

Evaluation of Sofosbuvir and Daclatasvir Combo in COIVD-19 Patients in Egypt

NCT04773756

Phase 4 Completed 54 enrolled Alexandria University
NaSingle-groupOpen-labelTreatment

Summary

Sofosbuvir has been recently recommended as a possible antiviral for COVID-19, based on structural studies and multiple alignment analysis. By comparing the positive-stranded RNA genomes of HCV and SARS-CoV-2, it has been postulated that sofosbuvir might be an optimal nucleotide analogue to repurpose for COVID-19 treatment

Timeline

Start
2020-11-01
Primary completion
2020-11-30
Completion
2020-12-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Daclatasvir Small molecule 60 mg
Subject Sofosbuvir Small molecule 400 mg

Indications