drugset / Trial / NCT04778839
Study of Paclitaxel Micelles for Injection in Chinese Patients With Advanced Solid Tumors.
Phase 1
Recruiting
98 enrolled
First Affiliated Hospital of Zhejiang University
Hangzhou Dihua Biotechnology Co., LTD. · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
A Phase I Study of Dose Escalation and Dose Expansion To Evaluate the Safety、Tolerability、Pharmacokinetics and Preliminary Efficacy of Paclitaxel Micelles for Injection in Chinese Patients With Advanced Solid Tumor.
Timeline
- Start
- 2021-03-04
- Primary completion
- 2026-06-30
- Completion
- 2026-06-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Paclitaxel | Small molecule | 175 mg/m2 | Intravenous |
| Comparator | Paclitaxel | Small molecule | 260 mg/m2 | Intravenous |
| Comparator | Paclitaxel | Small molecule | 320 mg/m2 | Intravenous |
| Comparator | Paclitaxel | Small molecule | 390 mg/m2 | Intravenous |