drugset / Trial / NCT04800159
Cannabis Effects on Antiretroviral Therapy Pharmacokinetics and Neurotoxicity
Phase 2
Active not recruiting
40 enrolled
University of California, San Diego
Center for Medicinal Cannabis Research · collab
RandomizedCrossoverQuadruple-blindBasic science
Summary
This study will address whether cannabis affects antiretroviral therapy (ART) drug concentrations, mood, and thinking. The project will have two phases. Phase 1 is an observational study, in which 120 people will be assessed to evaluate the effects of chronic cannabis use on ART drug concentrations, mood, and thinking. In Phase 2, the study will administer cannabis (or placebo) to 40 people to examine its acute effects on ART drug concentrations.
Timeline
- Start
- 2021-02-19
- Primary completion
- 2025-10-30
- Completion
- 2026-04-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cannabis | Traditional medicine (herbal / TCM) | — | Other |