Comparison of Temporomandibular Joint Arthroscopy With Botulinum Toxin Injection Versus Placebo

Summary

There are several studies that have considered Botulinum toxin A (BoNT-A) injections are effective in treating symptoms for Temporomandibular Joint (TMJ) disorders. BoNT-A injections improve the hyper-tonicity of mandibular muscles and its consequent joint load reduction. Also injections of BoNT-A, for patients with articular disc displacement, resulted in pain relief and return of the normal movements of the mandible. The main goal of this study is to test the beneficial impact of BoNT-A injections in the masticatory muscles of patients submitted to TMJ surgical arthroscopy.

Timeline

Start

2021-01-01

Primary completion

2021-12-31

Completion

2022-06-01

Drugs

Indications