drugset / Trial / NCT04841018

Does Low Dose of Dexamethasone Enhance Analgesic Quality of Caudal Analgesia in Children Undergoing Orchiopexy?

NCT04841018 ↗

Completed 273 enrolled Yonsei University
RandomizedParallel-groupTriple-blindPrevention

Summary

Caudal block is one of the most effective modalities to reduce pain both during and after the surgery involving areas under the umbilicus. According to previous research, 0.5mg/kg-1.5mg/kg dexamethasone is known to enhance the analgesic quality of caudal block in children. Despite the fact that this high dose of dexamethasone is used to treat airway edema in actual practice and no adverse side effect related to dosage has been reported, it is 3 to 15 times higher than the daily antiemetic dose of dexamethasone that is used in standard care of anesthesia. Therefore, our study aims to assess the effect of the more practical, antiemetic dose of dexamethasone (0.15mg/kg) as an adjuvant to enhance the quality of caudal block through a non-inferiority trial.

Timeline

Start
2021-03-24
Primary completion
2023-08-29
Completion
2023-09-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexamethasone Small molecule 0.15 mg/kg Intravenous
Subject Dexamethasone Small molecule 0.5 mg/kg Intravenous

Indications