drugset / Trial / NCT04847024

Parecoxib vs. Dexketoprofen for the Management of Pain After Cesarean Section.

NCT04847024

Completed 380 enrolled Saint Thomas Hospital, Panama
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Although it is known that parecoxib and dexketoprofen are commonly used in successful post-operative pain relief, there are very few studies that compare these two agents in their individual applications and/or combined with neuraxial analgesia with opioids and even less in post-cesarean section pain, as well as the evaluation of the side effects and their impact on the patient's functionality. For this reason, in order to approach this answer, we sought to perform this study in patients undergoing elective or emergency cesarean section in our institution, who meet the inclusion criteria, using the Visual Analog Pain Scale at 12 hrs and 24 hrs post surgery and evaluating the aforementioned side effects, comparing in one arm of the study Parecoxib + acetaminophen vs Dexketoprofen + acetaminophen in the other arm, randomizing the patients in both groups using a double-blind configuration.

Timeline

Start
2019-07-01
Primary completion
2019-09-30
Completion
2019-09-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexketoprofen Small molecule 50 mg Intravenous
Subject Parecoxib Small molecule 40 mg Intravenous

Indications

No indication recorded.