Drugs / Dexketoprofen
Dexketoprofen
also known as
Dexketoprofen Trometamol · arveles · DKP · (s)-ketoprofen · Dexketoprofen/Vitamin B · Dexketoprofene · Dexketoprofeno · Keral · +3 more
Trials 19 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 33 trials | ||||||
| Phase 3 | NCT06404177 | Jul 2023 → Aug 2024 | — | Riadh Boukef | Unknown | No outcome recorded |
| Phase 3 | NCT01904149 | May 2013 → May 2014 | — | Menarini Group | Completed | No outcome recorded |
| Phase 3 | NCT01902134 | Apr 2013 → Feb 2014 | — | Menarini Group | Completed | No outcome recorded |
| Phase 411 trials | ||||||
| Phase 4 | NCT06060236 | Sep 2023 → Sep 2024 | disease of bone structure | Ankara City Hospital Bilkent | Unknown | No outcome recorded |
| Phase 4 | NCT05657704 | Oct 2022 → Dec 2023 | — | Fundación de Investigación Biomédica - Hospital Universitario de La Princesa | Unknown | No outcome recorded |
| Phase 4 | NCT04533568 | Sep 2020 → Dec 2021 | migraine without aura | Kecioren Education and Training Hospital | Completed | No outcome recorded |
| Phase 4 | NCT04609254 | Dec 2018 → Apr 2020 | — | Pamukkale University | Completed | No outcome recorded |
| Phase 4 | NCT04372264 | Oct 2018 → May 2020 | migraine disorder | Pamukkale University | Unknown | No outcome recorded |
| Phase 4 | NCT03768882 | Dec 2017 → Jul 2018 | pharyngitis | Pamukkale University | Completed | No outcome recorded |
| Phase 4 | NCT02777970 | Apr 2016 → Feb 2017 | — | Menarini Group | Completed | No outcome recorded |
| Phase 4 | NCT03428503 | Dec 2015 → Dec 2016 | musculoskeletal system disorder | Pamukkale University | Completed | No outcome recorded |
| Phase 4 | NCT03122314 | Aug 2015 → Sep 2016 | musculoskeletal system disorder | Pamukkale University | Completed | No outcome recorded |
| Phase 4 | NCT02380001 | Jan → Aug 2015 | — | Daniel Chavarría Bolaños | Completed | No outcome recorded |
| Phase 4 | NCT01422291 | Jan → Jul 2011 | — | Pamukkale University | Completed | No outcome recorded |
| Phase not applicable5 trials | ||||||
| — | NCT07386288 | Nov 2024 → Apr 2025 | — | Ataturk University | Completed | No outcome recorded |
| — | NCT05176158 | Nov 2024 | congenital temporomandibular joint ankylosis, impacted teeth, multiple, inflammatory disease | Universidad Complutense de Madrid | Completed | No outcome recorded |
| — | NCT04252521 | Jul 2019 → Jan 2020 | migraine disorder | Adiyaman University Research Hospital | Completed | No outcome recorded |
| — | NCT04847024 | Jul → Sep 2019 | — | Saint Thomas Hospital, Panama | Completed | No outcome recorded |
| — | NCT05303688 | Mar → Oct 2018 | neuropathy, painful | TC Erciyes University | Completed | No outcome recorded |
Also used as a comparator or background therapy in 35 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT05027126 Comparator | Feb → Nov 2019 | — | Laboratorios Silanes S.A. de C.V. | Completed | No outcome recorded |
| Phase 22 trials | ||||||
| Phase 2 | NCT04161690 Comparator | Nov 2019 → Nov 2020 | — | KAT General Hospital | Unknown | No outcome recorded |
| Phase 2 | NCT04178109 Comparator | Jan → Nov 2019 | — | KAT General Hospital | Completed | No outcome recorded |
| Phase 2/32 trials | ||||||
| Phase 2/3 | NCT07057752 Comparator | Aug → Oct 2025 | peripheral arterial disease | Kastamonu University | Completed | No outcome recorded |
| Phase 2/3 | NCT06222320 Comparator | Jan → Oct 2024 | — | Kastamonu University | Completed | No outcome recorded |
| Phase 33 trials | ||||||
| Phase 3 | NCT05001555 Comparator | Nov 2021 → Apr 2023 | — | Laboratorios Silanes S.A. de C.V. | Completed | No outcome recorded |
| Phase 3 | NCT03585036 Comparator | Jul → Sep 2018 | — | Cairo University | Unknown | No outcome recorded |
| Phase 3 | NCT02602197 Comparator | Aug 2013 → Dec 2015 | — | Baskent University | Unknown | No outcome recorded |
| Phase 416 trials | ||||||
| Phase 4 | NCT06878014 Comparator | Mar 2025 → Jun 2026 overdue | — | Medical University of Silesia | Recruiting | No outcome recorded |
| Phase 4 | NCT06563271 Comparator | Dec 2023 → May 2024 | — | Ankara Etlik City Hospital | Completed | No outcome recorded |
| Phase 4 | NCT06916234 Comparator | Jan → Dec 2023 | periodontitis | ibrahim doğru | Completed | No outcome recorded |
| Phase 4 | NCT06540599 Comparator | Sep → Oct 2022 | — | Gaziosmanpasa Research and Education Hospital | Completed | No outcome recorded |
| Phase 4 | NCT06932367 Comparator | Aug 2021 → Aug 2022 | — | Ali Gur | Completed | No outcome recorded |
| Phase 4 | NCT04894864 Comparator | Oct 2020 → Sep 2026 expected | abdominal aortic aneurysm | University of Crete | Recruiting | No outcome recorded |
| Phase 4 | NCT05170841 Comparator | Sep 2020 → May 2022 | — | Menarini International Operations Luxembourg SA | Completed | No outcome recorded |
| Phase 4 | NCT05529290 Comparator | Jul 2019 → Jul 2021 | temporomandibular joint disorder | Yuzuncu Yil University | Completed | No outcome recorded |
| Phase 4 | NCT02929147 Comparator | Nov 2016 → Nov 2017 | supratentorial cancer | Istanbul University | Unknown | No outcome recorded |
| Phase 4 | NCT03865004 Comparator | Oct 2015 → Oct 2016 | urinary system disorder | Akdeniz University | Completed | No outcome recorded |
| Phase 4 | NCT02373514 Comparator | Jan → Mar 2015 | dysmenorrhea | Akdeniz University | Unknown | No outcome recorded |
| Phase 4 | NCT02285972 Comparator | Nov 2014 → Apr 2015 | — | Ordu University | Completed | No outcome recorded |
| Phase 4 | NCT02159547 Comparator | May → Aug 2014 | migraine disorder | Akdeniz University | Completed | No outcome recorded |
| Phase 4 | NCT02018601 Background | Sep 2013 → Dec 2021 | — | Paula Diéguez García | Unknown | No outcome recorded |
| Phase 4 | NCT02568735 Comparator | Jan 2013 → Dec 2014 | neuropathy, painful | Kuopio University Hospital | Completed | No outcome recorded |
| Phase 4 | NCT01730326 Comparator | Mar → Jul 2012 | migraine without aura | Pamukkale University | Completed | No outcome recorded |
| Phase not applicable11 trials | ||||||
| — | NCT07642674 Comparator | Jun 2026 → Jan 2027 expected | — | Eskisehir Osmangazi University | Recruiting | No outcome recorded |
| — | NCT07248540 Comparator | Jul 2025 → Jan 2026 overdue | dysmenorrhea | Havva Betül Bacak | Recruiting | No outcome recorded |
| — | NCT06978816 Background | Jun 2025 → Jun 2026 overdue | urinary system disorder | Gao Xiaofeng | Recruiting | No outcome recorded |
| — | NCT06222333 Comparator | Nov 2024 → Apr 2025 overdue | — | Kastamonu University | Recruiting | No outcome recorded |
| — | NCT07604376 Background | Mar 2024 → Jul 2026 overdue | — | Matild Keresztes | Recruiting | No outcome recorded |
| — | NCT07706036 Background | Jan → Jul 2024 | — | Ankara City Hospital Bilkent | Completed | No outcome recorded |
| — | NCT04582032 Comparator | Nov → Dec 2020 | — | Ankara City Hospital Bilkent | Completed | No outcome recorded |
| — | NCT03170726 Comparator | May → Oct 2017 | — | Erzincan University | Unknown | No outcome recorded |
| — | NCT03170713 Comparator | May → Oct 2017 | — | Erzincan University | Unknown | No outcome recorded |
| — | NCT02527603 Background | Aug 2015 → Mar 2017 | — | Corporacion Parc Tauli | Completed | No outcome recorded |
| — | NCT01638962 Comparator | Aug 2012 → Aug 2015 | osteoarthritis, knee | University of Southern Denmark | Completed | No outcome recorded |
Evidence & citations 15 cited values
Every value below carries the sentence it was read from. 56 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Dexketoprofen | “The primary objective of this study is to evaluate the effect of intravenous dexketoprofen administered during the postoperative period on the incidence and severity of rebound...” NCT07642674 ↗52“All patients will be administered a dose of NSAI intra-muscular or orally ("Dexketoprofen", "Enantyum®") it is part of the normal treatment of these patients to cope with pain.” NCT02527603 ↗ “800 mg ibuprofen and 50 mg dexketoprofen in 150 cc normal saline before operation will be given in 30 minutes.” NCT03170713 ↗ “Patients in the control group will receive conservative treatment consisting of paracetamol and dexketoprofen.” NCT06222333 ↗ “Patients in this group will be treated with painkillers consisting of paracetamol and dexketoprofen.” NCT06222320 ↗ “Intravenous infusion of 50 mg dexketoprofen trometamol injection” NCT06978816 ↗ “Paracetamol 1g +/- Dexketoprofen trometamol 50mg” NCT04894864 ↗ “Patients using oral dexketoprofen for analgesia” NCT06540599 ↗ “NSAIDs (ibuprofen, dexketoprofen, pareecoxib)” NCT07604376 ↗ “Dexketoprofen 25 mg” NCT05657704 ↗ “Dexketoprofen” NCT01638962 ↗ |
| Known as | (s)-ketoprofen | ChEMBL registry synonym — accepted as the source's own label CHEMBL75435 ↗ |
| Known as | arveles | “Second Group: dexketoprofen 50 mg ( arveles ampoule -Ufsa- Istanbul) intravenous (IV) was given 70 patients,” NCT04372264 ↗2“dexketoprofen 50 mg arveles 50 mg ampoule -Menarini- Istanbul) intravenous (IV) was given 70 patients,” NCT04609254 ↗ |
| Known as | Dexketoprofen Trometamol | “Study patients were randomised into two groups to receive either 50 mg of dexketoprofen trometamol or 1000 mg of paracetamol intravenously by rapid infusion in 150 mL of normal saline.” PMID 24394884 ↗ Jan 20145“Dexketoprofen trometamol, is one of the most powerful inhibitors of prostaglandin synthesis "in vitro".” NCT02380001 ↗ “fixed combination of dexketoprofen trometamol (DKP) and tramadol hydrochloride (TRAM)” NCT01902134 ↗ “Any known allergy or secondary reaction to piroxen or dexketoprofen trometamol.” NCT06404177 ↗ “Dexketoprofen Trometamol 50 Mg/mL Solution for Injection” NCT06563271 ↗ “Drug: Dexketoprofen Trometamol” NCT04161690 ↗ |
| Known as | Dexketoprofen/Vitamin B | ClinicalTrials.gov intervention name — accepted as the source's own label NCT05001555 ↗ |
| Known as | Dexketoprofene | ChEMBL registry synonym — accepted as the source's own label CHEMBL75435 ↗ |
| Known as | Dexketoprofeno | ChEMBL registry synonym — accepted as the source's own label CHEMBL75435 ↗ |
| Known as | DKP | “fixed combination of dexketoprofen trometamol (DKP) and tramadol hydrochloride (TRAM)” NCT01902134 ↗1“fixed combination of dexketoprofen trometamol (DKP) and tramadol hydrochloride (TRAM)” NCT01904149 ↗ |
| Known as | Keral | ChEMBL registry synonym — accepted as the source's own label CHEMBL75435 ↗ |
| Known as | KETAVEL | “Dexketoprofen (KETAVEL 50 mg/2 ml)” NCT06932367 ↗ |
| Known as | Metadem (dexketoprofen trometamol) | “Metadem (dexketoprofen trometamol)” NCT04252521 ↗ |
| Known as | neo ketadex 25 | “dexketoprofen 25mg (neo ketadex 25, Marcryl, Egypt)” NCT03585036 ↗ |
| Action | Inhibit | “Dexketoprofen trometamol, is one of the most powerful inhibitors of prostaglandin synthesis "in vitro".” NCT02380001 ↗ |
| Modality | Small molecule | “Dexketoprofen is a new NSAID treating acute postoperative pain.” NCT04161690 ↗ |
| Route | Intravenous | “single intravenous doses of paracetamol (1 g), dexketoprofen (50 mg) and morphine (0.1 mg/kg)” NCT01422291 ↗ |