drugset / Trial / NCT07706036

Naproxen and Lidocaine Gel Combination for Rib Fracture

NCT07706036

Completed 110 enrolled Ankara City Hospital Bilkent
RandomizedParallel-groupDouble-blindTreatment

Summary

This study evaluates whether adding a topical gel containing naproxen and lidocaine to routine intravenous analgesic treatment improves pain relief in adults with isolated traumatic rib fractures presenting to the emergency department. Participants are randomly allocated to receive either standard intravenous dexketoprofen alone or dexketoprofen combined with topical naproxen-lidocaine gel. Pain intensity is measured repeatedly during the first hour after treatment using the Numerical Rating Scale (NRS). The study also examines the need for additional rescue analgesia and monitors treatment-related adverse events to determine the effectiveness and safety of this multimodal analgesic strategy.

Timeline

Start
2024-01-01
Primary completion
2024-07-01
Completion
2024-07-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Lidocaine Other / unclassified 5 % Topical
Subject Naproxen Small molecule 10 % Topical
Background Dexketoprofen Small molecule 50 mg Intravenous

Indications

No indication recorded.