drugset / Trial / NCT07706036
Naproxen and Lidocaine Gel Combination for Rib Fracture
RandomizedParallel-groupDouble-blindTreatment
Summary
This study evaluates whether adding a topical gel containing naproxen and lidocaine to routine intravenous analgesic treatment improves pain relief in adults with isolated traumatic rib fractures presenting to the emergency department. Participants are randomly allocated to receive either standard intravenous dexketoprofen alone or dexketoprofen combined with topical naproxen-lidocaine gel. Pain intensity is measured repeatedly during the first hour after treatment using the Numerical Rating Scale (NRS). The study also examines the need for additional rescue analgesia and monitors treatment-related adverse events to determine the effectiveness and safety of this multimodal analgesic strategy.
Timeline
- Start
- 2024-01-01
- Primary completion
- 2024-07-01
- Completion
- 2024-07-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lidocaine | Other / unclassified | 5 % | Topical |
| Subject | Naproxen | Small molecule | 10 % | Topical |
| Background | Dexketoprofen | Small molecule | 50 mg | Intravenous |
Indications
No indication recorded.