drugset / Trial / NCT03865004

Combination Trial of Intravenous Paracetamol - Morphine for Treating Acute Renal Colic in Emergency Setting: An Optimum Treatment

NCT03865004

Phase 4 Completed 136 enrolled Akdeniz University
RandomizedParallel-groupSingle-blindTreatment

Summary

This randomized, placebo-controlled trial evaluated the analgesic efficacy and safety of intravenous morphine-paracetamol combination and morphine-dexketoprofen combination morphine for the optimum treatment of renal colic. Combination of IV morphine and paracetamol is as effective and rapid as combination of IV Morphine and IV dexketoprophen for optimum treating of renal colic.

Timeline

Start
2015-10-17
Primary completion
2016-10-17
Completion
2018-10-17

Drugs

EvaluationDrugModalityDoseRoute
Comparator Acetaminophen Small molecule 1 g Intravenous
Comparator Dexketoprofen Small molecule 75 mg Intravenous
Comparator Morphine Other / unclassified 0.1 mg/kg Intravenous