Evaluation of the Analgesic Efficacy of the Combination of Dexketoprofen + Paracetamol and the Combination of Naproxen Sodium + Codeine in Patients With Acute Dental Pain

Summary

Acute dental pain is one of the most challenging conditions to treat and manage in dental practice. The aim of this study was to compare the efficacy of naproxen sodium + codeine phosphate (550/30 mg) and dexketoprofen trometamol + paracetamol (25/300 mg) in the treatment of acute dental pain in individuals with acute pericoronitis caused by impacted wisdom teeth.

Timeline

Start

2023-01-10

Primary completion

2023-12-20

Completion

2024-01-20

Publications

• Dogru I, Cigerim L. Comparison of the analgesic efficacy of dexketoprofen trometamol and paracetamol with naproxen sodium and codeine phosphate combinations in acute toothache. Sci Rep. 2025 Oct 17;15(1):36381. doi: 10.1038/s41598-025-20361-7.

Drugs

Indications