drugset / Trial / NCT04178109

Oral Use of Dexketoprofen/Tramadol for Acute Postoperative Pain in Total Hip Replacement With a Direct Anterior Approach.

NCT04178109

Phase 2 Completed 226 enrolled KAT General Hospital
RandomizedParallel-groupSingle-blindTreatment

Summary

Pain is a global public health issue and represents the most common reason for both physician consultation and hospital admissions . When unrelieved or poorly controlled, it is associated with medical complications, poor patient satisfaction and increased risk of developing chronic pain. Dexketoprofen is a new NSAID treating acute postoperative pain and when it combined with tramadol may have a better effect. The purpose of this study is to evaluate the analgesic effect of the oral use of the combination of dexketoprofen/tramadole on the reduction of postoperative pain after total hip arthroplasty with minimal invasive anterior approach (AMIS).

Timeline

Start
2019-01-10
Primary completion
2019-11-10
Completion
2019-11-20

Drugs

EvaluationDrugModalityDoseRoute
Comparator Acetaminophen Small molecule 1 g Intravenous
Comparator Dexketoprofen Small molecule 27 mg Oral
Comparator Tramadol Other / unclassified 75 mg Oral
Comparator Levobupivacaine Other / unclassified 10 mg Other
Comparator Levobupivacaine Other / unclassified 15 mg Other
Comparator Ropivacaine Other / unclassified 300 mg Other

Indications

No indication recorded.