drugset / Trial / NCT04873297

Metoclopramide vs Placebo for Prevention of Pneumonia in Acute Stroke

NCT04873297

Phase 4 Completed 106 enrolled Shaheed Zulfiqar Ali Bhutto Medical University
RandomizedParallel-groupOpen-labelPrevention

Summary

Pneumonia is a major cause of mortality and morbidity in patients with acute stroke fed via nasogastric tubes and may be because of vomiting and gastro-esophageal regurgitation. The aim of the study was to assess whether regular treatment with metoclopramide, a D2-receptor antagonist with antiemetic and gastric prokinetic actions, could reduce the rate of pneumonia.

Timeline

Start
2021-05-02
Primary completion
2021-10-02
Completion
2021-10-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Metoclopramide Small molecule 10 mg Other