drugset / Trial / NCT04873297
Metoclopramide vs Placebo for Prevention of Pneumonia in Acute Stroke
RandomizedParallel-groupOpen-labelPrevention
Summary
Pneumonia is a major cause of mortality and morbidity in patients with acute stroke fed via nasogastric tubes and may be because of vomiting and gastro-esophageal regurgitation. The aim of the study was to assess whether regular treatment with metoclopramide, a D2-receptor antagonist with antiemetic and gastric prokinetic actions, could reduce the rate of pneumonia.
Timeline
- Start
- 2021-05-02
- Primary completion
- 2021-10-02
- Completion
- 2021-10-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Metoclopramide | Small molecule | 10 mg | Other |