drugset / Trial / NCT04875728

The Impact of an Antibiotic (Cefazolin) Before Surgery on the Microbiome in Patients With Stage I-II Melanoma

NCT04875728

RandomizedParallel-groupOpen-labelTreatment

Summary

This phase I trial investigates the impact of cefazolin before surgery on the microbiome in patients with stage I-II melanoma. Antibiotics, such as cefazolin, given at the time of surgery may cause a significant change in the microbes (like bacteria and viruses) found in the stomach and intestines. This trial may help researchers learn if any changes in microbes affect the body's ability to respond to surgery and cancer.

Timeline

Start
2020-09-08
Primary completion
2027-02-02
Completion
2027-02-02

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cefazolin Small molecule Intravenous

Indications