Safety and Efficacy of Esmketamine Versus Dexmedetomidine

Phase 4 Unknown 80 enrolled Zhongnan Hospital

RandomizedSequentialSingle-blindOther

Summary

A comparative study on the safety and efficacy of esmketamine versus Dexmedetomidine during drug induced sleep endoscopy in children with positional obstructive sleep apnea: A consort-prospective, randomized, controlled clinical trial

Timeline

Start: 2021-05-01
Primary completion: 2022-12-01
Completion: 2023-05-01

Publications

Yongping Z, Xinyi L, Aming S, Qiang X, Tianqi Z, Mengmeng S, Xiong C, Xuemin S. The safety and efficacy of esketamine in comparison to dexmedetomidine during drug-induced sleep endoscopy in children with obstructive sleep apnea hypopnea syndrome: A randomized, controlled and prospective clinical trial. Front Pharmacol. 2022 Dec 1;13:1036509. doi: 10.3389/fphar.2022.1036509. eCollection 2022.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Dexmedetomidine	Other / unclassified	1 ug/kg	Intravenous
Comparator	Esmketamine	Unknown	1 mg/kg	Intravenous

Indications

No indication recorded.