drugset / Trial / NCT04879121

Larotrectinib for the Treatment of NTRK Amplification Positive, Locally Advanced or Metastatic Solid Tumors

NCT04879121

NaSingle-groupOpen-labelTreatment

Summary

This phase II trial studies the effect of larotrectinib in treating patients with NTRK gene amplification positive solid tumors that have spread to nearby tissues or lymph nodes (locally advanced) or other places in the body (metastatic). Larotrectinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Timeline

Start
2021-04-30
Primary completion
2027-11-11
Completion
2027-11-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Larotrectinib Small molecule Oral