drugset / Trial / NCT04884893
Effect of Nitrous Oxide on EEG
Phase 1
Completed
20 enrolled
Tampere University Hospital
Tampere University · collabUniversity of Helsinki · collab
RandomizedParallel-groupDouble-blindBasic science
Summary
Our recent preclinical observations suggest that monitoring of slow electroencephalogram (EEG) oscillations may be used to predict the efficacy of rapid-acting antidepressants such as ketamine or nitrous oxide. In this project we will carry out critical clinical research on healthy volunteers and study the effects of nitrous oxide on EEG. Results will be used for the design of clinical trials on depressed individuals. The project will be done in collaboration between neuroscientists at the University of Helsinki and clinicians at the Tampere University Hospital.
Timeline
- Start
- 2021-05-21
- Primary completion
- 2021-09-24
- Completion
- 2021-09-24
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Nitrous Oxide | Other / unclassified | 50 % | — |
Indications
No indication recorded.