drugset / Trial / NCT04886167
Dysport Dose-Ranging Treatment of Platysmal Bands
RandomizedSequentialDouble-blindTreatment
Summary
This is a double-blinded, dose-ranging study in the US to assess the efficacy, safety, and duration of response of abobotulinumtoxinA for the treatment of moderate to severe platysmal bands.
Timeline
- Start
- 2021-05-30
- Primary completion
- 2022-11-01
- Completion
- 2022-11-01
Publications
- Background Monheit GD, Pickett A. AbobotulinumtoxinA: A 25-Year History. Aesthet Surg J. 2017 May 1;37(suppl_1):S4-S11. doi: 10.1093/asj/sjw284.
- Background Carruthers J, Carruthers A. The evolution of botulinum neurotoxin type A for cosmetic applications. J Cosmet Laser Ther. 2007 Sep;9(3):186-92. doi: 10.1080/14764170701411470.
- Background Matarasso A, Matarasso SL, Brandt FS, Bellman B. Botulinum A exotoxin for the management of platysma bands. Plast Reconstr Surg. 1999 Feb;103(2):645-52; discussion 653-5. doi: 10.1097/00006534-199902000-00043.
- Background Brandt FS, Bellman B. Cosmetic use of botulinum A exotoxin for the aging neck. Dermatol Surg. 1998 Nov;24(11):1232-4. doi: 10.1111/j.1524-4725.1998.tb04103.x.
- Background Kane MA. Nonsurgical treatment of platysmal bands with injection of botulinum toxin A. Plast Reconstr Surg. 1999 Feb;103(2):656-63; discussion 664-5. doi: 10.1097/00006534-199902000-00045.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Botulinum toxin type A | Protein / enzyme biologic | 120 iu | Intramuscular |
| Comparator | Botulinum toxin type A | Protein / enzyme biologic | 180 iu | Intramuscular |
| Comparator | Botulinum toxin type A | Protein / enzyme biologic | 240 iu | Intramuscular |
Indications
No indication recorded.