drugset / Trial / NCT04890626

Clinical Trial to Evaluate the Efficacy of Different Treatments in Patients With COVID-19

NCT04890626

RandomizedParallel-groupOpen-labelTreatment

Summary

Currently COVID-19 is an international public health emergency. Most COVID-19 patients have mild or uncomplicated disease, but approximately 14% develop severe disease that requires hospitalization and oxygen therapy, and up to 5% of patients require admission to Intensive Care Units. To date, the only treatments that have shown efficacy in a clinical trial are remdesivir and dexamethasone. The main objective is to provide reliable estimates on the effects of different treatment strategies on the outcome and mortality of patients with SARS-CoV-2 infection.

Timeline

Start
2020-04-04
Primary completion
2023-07-17
Completion
2023-07-17

Drugs

EvaluationDrugModalityDoseRoute
Subject Baricitinib Small molecule
Subject Tenofovir disoproxil fumarate Small molecule 245 mg Oral
Subject emtricitabine Other / unclassified 200 mg Oral
Background Dexamethasone Small molecule

Indications