drugset / Trial / NCT04890626
Clinical Trial to Evaluate the Efficacy of Different Treatments in Patients With COVID-19
RandomizedParallel-groupOpen-labelTreatment
Summary
Currently COVID-19 is an international public health emergency. Most COVID-19 patients have mild or uncomplicated disease, but approximately 14% develop severe disease that requires hospitalization and oxygen therapy, and up to 5% of patients require admission to Intensive Care Units. To date, the only treatments that have shown efficacy in a clinical trial are remdesivir and dexamethasone. The main objective is to provide reliable estimates on the effects of different treatment strategies on the outcome and mortality of patients with SARS-CoV-2 infection.
Timeline
- Start
- 2020-04-04
- Primary completion
- 2023-07-17
- Completion
- 2023-07-17
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Baricitinib | Small molecule | — | — |
| Subject | Tenofovir disoproxil fumarate | Small molecule | 245 mg | Oral |
| Subject | emtricitabine | Other / unclassified | 200 mg | Oral |
| Background | Dexamethasone | Small molecule | — | — |