drugset / Trial / NCT04897217

Levonorgestrel-Releasing Intrauterine System (LNG-IUS) in the Management of Atypical Endometrial Hyperplasia

NCT04897217

RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this research study is to compare the uterus tissue of women who receive an intrauterine system to treat their endometrial hyperplasia with the uterine tissue of women who receive megestrol acetate to treat their hyperplasia. While both methods are commonly used in practice, investigators would like to see what effects each treatment has on uterine tissue.

Timeline

Start
2023-06-30
Primary completion
2024-10
Completion
2026-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Levonorgestrel Small molecule 20 ug Other
Comparator Megestrol Acetate Other / unclassified 160 mg Oral