Pre-emptive Dexamethasone in Hip Arthroplasty
Summary
* Certain studies suggested that preoperative administration of systemic glucocorticoids in patients undergoing hip or knee arthroplasty surgery may improve the postoperative analgesia owing to their anti-inflammatory effect. * This study will be carried out on 70 adult patients aged 21 to 75 years admitted to orthopedic operating rooms in Tanta university hospitals for hip surgery under spinal anesthesia. Informed written consent will be obtained from each participant. * Patients will be randomly distributed into two equal groups using the computer-generated software. * Control Group: (35 patients) Those patients will receive 10 ml of normal saline before surgery. * Dexamethasone Group: (35 patients) Those patients will receive 16 mg dexamethasone in 10 ml of normal saline before surgery. * Primary outcome will be postoperative morphine consumption and the secondary outcome will be the postoperative pain score
Timeline
- Start
- 2021-05-23
- Primary completion
- 2023-01-28
- Completion
- 2023-01-28
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexamethasone | Small molecule | 16 mg | — |
Indications
No indication recorded.