drugset / Trial / NCT04905563
NSAIDs vs Opioids for Post-op Pain in Supracondylar Humerus Fractures
RandomizedParallel-groupTriple-blindSupportive care
Summary
The purpose of this study is to determine if using the combination of acetaminophen (also known as Tylenol) and ibuprofen (also known as Motrin or Advil) will provide equal or better pain control as compared to acetaminophen-hydrocodone (also known as Lortab), in children with broken elbows who need surgery. This study will examine whether the combination of acetaminophen and ibuprofen can provide pain control as well as or better than acetaminophen-hydrocodone so that doctors might be able to prescribe less acetaminophen-hydrocodone (which can be addictive) to children in the future. Currently, the standard of care for pain control following this kind of elbow surgery is acetaminophen-hydrocodone.
Timeline
- Start
- 2021-06-07
- Primary completion
- 2024-01-05
- Completion
- 2024-01-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Acetaminophen | Small molecule | 15 mg/kg | — |
| Subject | Hydrocodone | Unknown | — | — |
| Subject | Ibuprofen | Small molecule | 10 mg/kg | — |
Indications
No indication recorded.