drugset / Trial / NCT04906304
Comparison of Safety and Efficacy of de Novo Everolimus
RandomizedParallel-groupSingle-blindTreatment
Summary
Nowadays, de novo everolimus regimen in renal transplant patients is considered for reduction of cyclosporine dose and it is mentioned that this regimen not only has similar safety and efficacy, but also could prevent Cytomegalovirus (CMV )infections. So, the aim of this study was comparison of safety and efficacy of de novo everolimus plus low dose of cyclosporine with standard dose of cyclosporine plus cellcept on CMV virus infections prevention in renal transplant patients.
Timeline
- Start
- 2020-01-01
- Primary completion
- 2020-07-01
- Completion
- 2020-08-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cyclosporine | Peptide | — | — |
| Subject | Everolimus | Small molecule | 0.75 mg | — |
| Background | Mycophenolate Mofetil | Small molecule | — | — |