drugset / Trial / NCT04906304

Comparison of Safety and Efficacy of de Novo Everolimus

NCT04906304

RandomizedParallel-groupSingle-blindTreatment

Summary

Nowadays, de novo everolimus regimen in renal transplant patients is considered for reduction of cyclosporine dose and it is mentioned that this regimen not only has similar safety and efficacy, but also could prevent Cytomegalovirus (CMV )infections. So, the aim of this study was comparison of safety and efficacy of de novo everolimus plus low dose of cyclosporine with standard dose of cyclosporine plus cellcept on CMV virus infections prevention in renal transplant patients.

Timeline

Start
2020-01-01
Primary completion
2020-07-01
Completion
2020-08-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Cyclosporine Peptide
Subject Everolimus Small molecule 0.75 mg
Background Mycophenolate Mofetil Small molecule