drugset / Trial / NCT04915365
Effect of Acetazolamide on Right Heart Function at Rest in Lowlanders With COPD Traveling to High Altitude
Phase 3
Unknown
100 enrolled
University of Zurich
National Center of Cardiology and Internal Medicine, Kyrgyz Republic · collab
RandomizedParallel-groupOpen-labelPrevention
Summary
The purpose of this randomized, placebo-controlled double-blind trial is to evaluate the effect of acetazolamide on right heart function at rest in lowlanders with chronic obstructive pulmonary disease (COPD) traveling to high altitude (HA) and developing early signs of altitude-illness.
Timeline
- Start
- 2021-05-01
- Primary completion
- 2022-12-31
- Completion
- 2023-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Acetazolamide | Small molecule | 125 mg | Oral |
| Subject | Acetazolamide | Small molecule | 250 mg | Oral |