drugset / Trial / NCT04919850

Effect of 60-days Saccharomyces Boulardii and Superoxide Dismutase Supplementation in Obese Adults

NCT04919850

RandomizedParallel-groupDouble-blindTreatment

Summary

In animals it has been demonstrated that Saccharomyces boulardii decrease low-grade inflammation and fat mass; also Superoxide Dismutase (SOD) decrease low-grade inflammation. Therefore, the aim of this double-blind, placebo-controlled clinical trial was to assess the effect of a 60-days S. boulardii and SOD supplementation on circulating markers of inflammation, body composition, hunger sensation, pro/antioxidant ratio, hormonal, lipid profile, glucose, insulin and HOMA-IR, in obese adults (BMI 30-35 kg/m2).

Timeline

Start
2018-01-15
Primary completion
2018-01-28
Completion
2020-06-20

Drugs

EvaluationDrugModalityDoseRoute
Subject ORGOTEIN Protein / enzyme biologic 500 iu
Subject Saccharomyces boulardii Other / unclassified 250 mg

Indications