drugset / Trial / NCT04919850
Effect of 60-days Saccharomyces Boulardii and Superoxide Dismutase Supplementation in Obese Adults
RandomizedParallel-groupDouble-blindTreatment
Summary
In animals it has been demonstrated that Saccharomyces boulardii decrease low-grade inflammation and fat mass; also Superoxide Dismutase (SOD) decrease low-grade inflammation. Therefore, the aim of this double-blind, placebo-controlled clinical trial was to assess the effect of a 60-days S. boulardii and SOD supplementation on circulating markers of inflammation, body composition, hunger sensation, pro/antioxidant ratio, hormonal, lipid profile, glucose, insulin and HOMA-IR, in obese adults (BMI 30-35 kg/m2).
Timeline
- Start
- 2018-01-15
- Primary completion
- 2018-01-28
- Completion
- 2020-06-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | ORGOTEIN | Protein / enzyme biologic | 500 iu | — |
| Subject | Saccharomyces boulardii | Other / unclassified | 250 mg | — |