drugset / Trial / NCT04926155

The Effect of Metformin in Patients With Metastatic Castration-resistant Prostate Cancer

NCT04926155 ↗

Phase 2 Unknown 234 enrolled Sun Yat-sen University
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to assess the effect of the addition of metformin to abiraterone on survival in patients with metastatic castration-resistant prostate cancer (mCRPC). The half the patients will receive metformin in combination with androgen deprivation therapy (ADT) and abiraterone, and the other half will receive ADT and abiraterone only.

Timeline

Start
2021-06-23
Primary completion
2024-04-30
Completion
2024-08-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Metformin Small molecule 2000 mg Oral