drugset / Trial / NCT04926155
The Effect of Metformin in Patients With Metastatic Castration-resistant Prostate Cancer
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to assess the effect of the addition of metformin to abiraterone on survival in patients with metastatic castration-resistant prostate cancer (mCRPC). The half the patients will receive metformin in combination with androgen deprivation therapy (ADT) and abiraterone, and the other half will receive ADT and abiraterone only.
Timeline
- Start
- 2021-06-23
- Primary completion
- 2024-04-30
- Completion
- 2024-08-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Metformin | Small molecule | 2000 mg | Oral |